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Job Summary

The Talkowski Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) and the Broad Institute of MIT and Harvard is seeking a highly motivated, enthusiastic Bioinformatics Specialist to work with and support our research group in analyzing sequencing data to identify structural variants within the human genome using genomic population databases and aggregating phenotype and genotype datasets.

We are comprised of an interdisciplinary group of scientists, technicians, bioinformaticians, computational biologists, and postdoctoral fellows who work together in a mutually supportive and respectful environment. Ideas are freely shared, and contributions are highly valued. We are dedicated to characterizing genomic variation contributing to human disease, with a focus on the relationship between genome structure and function. The lab integrates molecular and computational genomics methods to investigate the genetic architecture of neuropsychiatric disorders and develop new technologies for translational applications in genetic diagnostics. The lab has served as a hub for novel gene and variant discovery and functional genomics modeling in common complex and rare Mendelian disorders.

We are seeking a candidate to perform high-quality, large-scale computational analyses under the group leader's supervision in a timely manner. Successful candidates are expected to excel at critical thinking, be quick learners of new analytical approaches, and be able to apply or develop novel computational methods to solve complex problems. Candidates should have practical experience with programming languages, such as Java, C++, R, and/or Python. Must also have experience with computational analysis, algorithm development, and statistical analysis. Knowledge of existing bioinformatics analysis tools, methods, and databases is a significant plus.

This position is hybrid, and candidates can work remotely as needed.

Please note, the functions below are representative of major duties that are typically associated with these positions. Specific responsibilities may vary based upon departmental needs. Similarly, not all duties that have been outlined will be assigned to each position.

Essential Functions:

Assist in the analysis of biological data using bioinformatics tools and software.
Perform data processing, quality control, and database maintenance.
Collaborate with research teams to understand their data analysis needs. Support the development and implementation of data analysis pipelines. Conduct basic statistical analyses and data visualization.
Participate in the interpretation and presentation of results.

Working under very general supervision, the Bioinformatics Analyst will have demonstrated independent design and innovation in one or more of the following areas of specialization: algorithm development, data analysis, quality assurance/testing, pipeline software/computing development, user interface design & report development, web-based application development, or report development.

Required for All Jobs

Performs other duties as assigned Complies with all policies and standards

Does this position require Patient Care (indirect/direct)? No

Qualifications

Education
Bachelor's Degree Computational Biology required or Bachelor's Degree Related Field of Study required or Master's Degree Related Field of Study preferred

Can this role accept experience in lieu of a degree?
Yes

Licenses and Credentials

Experience
Computational Sciences Experience 0-1 year preferred

Knowledge, Skills and Abilities
- Demonstrated experience in infrastructure, programming languages, and computational sciences.
- Demonstrated ability working with open-source bioinformatics software.
- Possess strong analytical skills, including critical thinking, data modeling, problem solving, and troubleshooting.
- Strong organizational and interpersonal skills.
- Ability to effectively communicate, both orally and in writing, to all levels of staff.
- Excellent time management skills.

Additional Job Details (if applicable)

Remote Type

Hybrid

Work Location

185 Cambridge Street

Scheduled Weekly Hours

Employee Type

Regular

Work Shift

Day (United States of America)

Pay Range

$75,275.20 - $109,553.60/Annual

Grade

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

EEO Statement:

1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

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Bioinformatician I

Mass General Brigham Competency Framework