Site: The General Hospital Corporation

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

The MGB Tumor Cartography Core is a translational research facility focused on understanding cancer biology through advanced protein and RNA biomarker staining, high-plex imaging, and quantitative digital microscopy. As part of the Mass General Brigham Cancer Institute, we collaborate closely with researchers across MGH, BWH, and partner institutions. Our mission is to accelerate cancer research using cutting-edge spatial imaging and spatial transcriptomic technologies combined with state-of-the-art analytical tools.

We are seeking a motivated, detail-oriented individual who is excited to learn and grow in a dynamic research environment. This role is ideal for recent graduates who are interested in computational biology, digital pathology, biostatistics, image analysis, transcriptomics, or related fields.

- Apply existing and novel algorithms to various project data sets, critically review and analyze results

· Design and develop analysis approaches and workflows and novel software tools for large data sets from different sources

· Present results effectively to clinicians, experimental and computational scientists

· Quantitative digital image analysis: contribute to the downstream computational analysis pipelines quantitating digital images under the supervision of a staff or faculty member. Contributions will also include: assisting with hypothesis generation, experimental design, and data interpretation.

· Quantification and interpretation of spatial transcriptomics data using established analytic pipelines as well as work to develop new methods exploring basic biology of disease

· Other responsibilities include assisting the Tumor Cartography Core Manager in the maintenance and operation of imaging platforms in the group. Common tasks include training new users on advanced microscopy systems and performing image analysis using high-end commercial analysis software and computational languages such as R or Python.

Opportunities for candidate to work with cutting-edge spatial proteomic and transcriptomic platforms are also available. These skills can be learned on the job.

Job Summary

Responsible for combining research in biology, medicine, and health-related studies with information technology in order to collect and interpret data covering a range of fields, such as genetics or pharmaceutics. They create mathematical models, develop dynamic simulations, and perform pattern analyses of biological systems.

Does this position require Patient Care? No

Essential Functions
-Assist in the analysis of biological data using bioinformatics tools and software.

-Perform data processing, quality control, and database maintenance.

-Collaborate with research teams to understand their data analysis needs.

-Support the development and implementation of data analysis pipelines.

-Conduct basic statistical analyses and data visualization.

-Participate in the interpretation and presentation of results.

-Working under very general supervision, the Bioinformatics Analyst will have demonstrated independent design and innovation in one or more of the following areas of specialization: algorithm development, data analysis, quality assurance/testing, pipeline software/computing development, user interface design & report development, web-based application development, or report development.

Qualifications

Education
Bachelor's Degree Computational Biology required or Bachelor's Degree Related Field of Study required or Master's Degree Related Field of Study preferred

Can this role accept experience in lieu of a degree? Yes

Licenses and Credentials

Experience
Computational Sciences Experience 0-1 year preferred

Knowledge, Skills and Abilities
- Demonstrated experience in infrastructure, programming languages, and computational sciences.
- Demonstrated ability working with open-source bioinformatics software.
- Possess strong analytical skills, including critical thinking, data modeling, problem solving, and troubleshooting.
- Strong organizational and interpersonal skills.
- Ability to effectively communicate, both orally and in writing, to all levels of staff.
- Excellent time management skills.

Additional Job Details (if applicable)

Remote Type

Hybrid

Work Location

149 Thirteenth Street Building 149

Scheduled Weekly Hours

Employee Type

Regular

Work Shift

Day (United States of America)

Pay Range

$75,275.20 - $109,553.60/Annual

Grade

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

EEO Statement:

1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

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Bioinformatician I

Mass General Brigham Competency Framework

Bioinformatician I