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Alcon is looking to hire a Bioanalytical Scientist (Sr. Associate I) within, Preclinical Development to lead bioanalytical strategy supporting small‑molecule discovery, preclinical and regulatory development programs. This role serves as a key scientific interface across internal stakeholders and external partners, providing expert guidance on bioanalytical method development, execution, and interpretation for small‑molecule programs. The successful candidate will bring strong technical expertise, strategic thinking, and hands‑on leadership to ensure high‑quality, fit‑for‑purpose bioanalytical support aligned with program and regulatory needs.

This role is on-site in our Durham, NC location and a typical day will include:

Define and drive small‑molecule bioanalytical strategy across discovery, preclinical, and early clinical development.
Provide expert input on study design, method selection, data interpretation, and regulatory expectations for small‑molecule programs.
Develop and implement stage‑appropriate LC‑MS/MS‑based bioanalytical methods for quantification of small molecules in a variety of biological matrices.
Apply advanced analytical and separation techniques to address complex scientific questions related to exposure, metabolism, stability, and biotransformation.
Identify, evaluate, and implement new technologies and workflows to enhance bioanalytical efficiency and data quality.
Author and review bioanalytical sections of reports supporting INDs, regulatory submissions, patents, and publications.
Serve as the bioanalytical scientific representative on cross‑functional project teams, including partnered programs.
Analyze, interpret, and clearly communicate bioanalytical and DMPK data to project teams, senior leadership, and external collaborators.
Ensure consistent data quality, integrity, and documentation in accordance with GLP/GCP expectations and internal standards.
Contribute to continuous improvement of bioanalytical processes, infrastructure, and resource planning.

What you’ll bring to Alcon:

Bachelor’s Degree or Equivalent years of directly related experience (or high school +10 yrs; Assoc.+6 yrs; M.S.+0 yrs)
The ability to fluently read, write, understand and communicate in English.
2 Years of Relevant Experience.

Preferred Qualifications:

5+ Years of Relevant Experience
Demonstrated expertise in LC‑MS/MS and mass‑spectrometry‑based quantitative bioanalysis.
Strong background in separation science and hyphenated analytical techniques.
Experience operating in regulated environments, with working knowledge of GLP/GCP requirements.
Proven ability to provide scientific leadership across multiple programs and priorities.
Strong written and verbal communication skills with the ability to convey complex data to diverse audiences.

Experience overseeing CROs and outsourced small‑molecule bioanalytical programs.
Familiarity with Phoenix WinNonlin for noncompartmental and PK data analysis.
Working knowledge of ocular PK modeling approaches and ophthalmology‑relevant modeling tools (e.g., ocular compartmental models, exposure–response interpretation).
Track record of innovation and modernization of bioanalytical workflows.

HOW YOU CAN THRIVE:

See your career like never before with focused growth and development opportunities
Join Alcon’s mission to provide outstanding, innovative products and solutions to improve sight, improve lives, and grow your career!
Alcon provides a robust benefits package including health, life, retirement, flexible time off and much more.
Travel up to 10%
Sponsorship - No
Relocation – No

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ALCON IS AN EQUAL OPPORTUNITY EMPLOYER AND PARTICIPATES IN E-VERIFY

Alcon takes pride in maintaining an inclusive environment that values different perspectives and our policies are non-discriminatory in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Alcon is also committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an email to alcon.recruitment@alcon.com and let us know the nature of your request and your contact information.

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