Director of Product Management - Commercial - #4563

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

GRAIL is seeking a Director, Software Product Management, Commercial Software to lead the strategy, roadmap, and execution of our commercial software portfolio. This leader will play a critical role in shaping the systems that power our commercial operations and enable healthcare providers, patients, and partners to access and adopt our life-saving technologies. You will join a cross-functional organization spanning engineering, commercial, laboratory operations, billing, legal, quality, and finance to deliver scalable, secure, and compliant software solutions in a highly regulated clinical environment.

This role requires both strategic vision and operational rigor — someone who can define long-term product direction while driving disciplined execution, balancing customer experience, commercial outcomes, and regulatory requirements.

This role is based in Menlo Park, California, and will move to Sunnyvale, California in Fall 2026. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 40% requirement for the site. At our Menlo Park campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities.

• Own the product vision and multi-year roadmap for GRAIL’s commercial software portfolio, aligning strategy to company objectives and market needs
• Serve as the senior product leader across commercial software initiatives, representing product in cross-functional leadership forums
• Develop deep understanding of provider, patient, and internal commercial workflows, including billing, reimbursement, and revenue cycle management
• Translate customer, stakeholder, and regulatory requirements into clear product requirements and prioritized backlogs
• Lead end-to-end product development from discovery and design through launch and iteration
• Partner closely with engineering, program management, design, quality, legal, and compliance to deliver secure, reliable, and scalable solutions
• Ensure adherence to FDA design controls, privacy regulations (HIPAA/GDPR), and internal quality standards
• Evaluate business tradeoffs and communicate product decisions effectively across executive and operational stakeholders
• Build, mentor, and scale a high-performing team of software product managers
• Establish metrics and feedback loops to measure product performance and drive continuous improvement

• 10+ years of product management experience in healthcare IT, life sciences, diagnostics, or other regulated industries
• 3+ years of experience directly managing and developing product managers
• Experience leading software products subject to FDA design controls and HIPAA compliance requirements
• Experience supporting billing, reimbursement, and revenue cycle management workflows
• Experience integrating software platforms with EMRs and/or CRMs
• Demonstrated ability to lead through ambiguity, influence without authority, and drive alignment across cross-functional teams
• Proven ability to prioritize strategically, negotiate scope, and deliver measurable business outcomes
• BS in a technical, scientific, engineering, or quantitative discipline or equivalent experience

• Experience building provider-facing, laboratory, or clinical workflow software
• Experience developing platforms that integrate with third-party systems, partners, and enterprise ecosystems
• Familiarity with GDPR and global data privacy considerations
• Domain knowledge in liquid biopsy or molecular diagnostics
• Experience scaling commercial software platforms in high-growth healthcare organizations
• Advanced degree (MS, MBA, PhD, or equivalent) in a relevant fiel

The expected, full-time, annual base pay scale for this position is $224K-$321K.

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at rc@grailbio.com if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!