Bioinformatics Technician, Shah Lab

The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe.

Bioinformatics Technician – Shah Lab

Exciting Opportunity at MSK:
MSK’s Computational Oncology Service is seeking a highly motivated and technically skilled Bioinformatics Technician to support innovative research within the laboratory of Dr. Sohrab Shah, Chief of Computational Oncology. The Shah Lab develops and applies advanced computational methods to understand the biology, evolution, and treatment response of cancer. This role offers the opportunity to contribute to impactful research by supporting data analysis, developing workflows, and collaborating closely with computational and experimental scientists across MSK.

The Shah Lab integrates large-scale sequencing, single-cell profiling, mathematical modeling, and machine learning to advance precision oncology. As a member of this dynamic research environment, you will help drive data-intensive projects, ensure scientific rigor, and facilitate smooth operational workflows within an interdisciplinary team.

Role Overview:

• Support research initiatives by developing, optimizing, and maintaining computational pipelines for genomic, transcriptomic, and single-cell datasets

• Conduct quality control, preprocessing, and analysis of high-throughput sequencing data (e.g., whole-genome, RNA-seq, ATAC-seq, single-cell -omics)

• Apply statistical, algorithmic, and machine learning approaches to extract biological insights

• Collaborate with researchers to troubleshoot analyses, implement bioinformatics tools, and support ongoing studies

• Document workflows, maintain code repositories, and contribute to reproducible research standards

• Assist in generating figures, summaries, and data presentations for internal review bodies and scientific publications

• Participate in lab meetings, cross-functional collaborations, and computational review sessions

Requirements:

• Bachelor’s degree in Bioinformatics, Computational Biology, Computer Science, or a related field (Master’s preferred but not required)

• Strong programming skills in Python and/or R

• Experience working with next-generation sequencing data and associated tools

• Familiarity with commonly used bioinformatics software, reference databases, and workflow managers

• Ability to analyze, summarize, and clearly communicate scientific findings

• Demonstrated capacity to collaborate within multidisciplinary scientific teams

• Experience in cancer genomics or large-scale data analysis is a plus

Core Skills:

• Analytical Thinking: Able to interpret complex datasets and troubleshoot computational challenges

• Technical Rigor: Commitment to reproducibility, data integrity, and methodological accuracy

• Communication: Skilled at explaining computational approaches and results to varied scientific audiences

• Teamwork: Collaborative approach and strong interpersonal skills

• Organization: Able to manage multiple ongoing projects and prioritize time-sensitive tasks

• Learning Agility: Ability to rapidly learn new tools, methods, and biological concepts

Additional Information:

• Schedule: Monday - Friday, 37.5 hours

• Location: 321 E. 61st Street, NYC

• Reporting to: Sohrab Shah

Helpful Links:

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Closing:

At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills.

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.  

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