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Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.Â
About the Role:
To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening, the Post Deployment Development Team is seeking a highly motivated Engineer to help support the evolution of the Guardant Health Shield product/assay from its current state into a high throughput production line. Â The Staff Engineer, position will contribute to analyzing current Shield operations workflows and recommend areas for process improvements. This role is based in Redwood City, CA and Palo Alto, CA.
As a Staff Engineer, you will support Shield Clinical Lab Operations and interface cross functionally with members of various departments including Technology Development, Quality Assurance, Bioinformatics, Continuous Improvement, and Automation Clinical Development. This position will be responsible for developing, maintaining and using process monitoring tools to continuously improve the performance of our tests, generating regulatory compliant scale-up, Verification/Validation, and tech transfer procedures, the development and validation of process changes to enhance Shield performance, and leading efforts to integrate automation, LIMS, and Technology Development to improve the operations of the clinical laboratory. An ideal candidate would have a high level of knowledge of Assay/Process/Method development and good documentation practice (GDP).
Essential Duties and Responsibilities:
Act as a strategic liaison between Operations, Technology Development, Automation, and other cross-functional partners to drive alignment and execution.
Lead or contribute to the design, development, optimization, and implementation of automated liquid handling processes, systems, and streamlined workflows.
Program robotic liquid handling workstations and integrated robotic systems.Â
Drive continuous improvement within Screening Operations by analyzing workflows, identifying bottlenecks, and developing solutions to reduce test turnaround time, reduce COGS, and improve efficiency, and product quality.Â
Solve practical problems and deal with a variety of concrete variables in situations where only limited standardization exists.
Advocate for the needs of the Lab Operations department.
Collaborate with all functions within project teams.
Drive collection of process requirements from cross-functional stakeholders.Â
Develop and present updates, author protocols, reports, and SOPs.
Support a Quality first culture by initiating and supporting the improvement and continuation of initiatives driving accuracy and consistent adherence to regulations.
Have a ‘change-agent’ mindset.
Essential Qualifications:
BS degree in engineering or science, preferably in bioengineering, chemical engineering, molecular biology, genetics, biochemistry, or a related discipline, and 8+ years of related experience. MS with 6+ years of related work experience or a PhD with 3+ years of related work experience will also be considered.Â
Must be able to work cross functionally in teams, or with individuals, on designated projects, to help clients and operators achieve sustainable results.
Experience in streamlining workflows and developing automated laboratory processes and instrumentation systems, including collecting and documenting requirements, developing concepts, assessing multiple proposals and choosing the one with the highest chance of success, design, testing/validation, implementing, and training.
Experience with operating and programming liquid handling robotics platforms (Hamilton, TECAN, Beckman, Agilent).
Experience with standard molecular biology techniques such as nucleic acid isolation, purification and quantitation, bioanalyzer, DNA/RNA quantitation, qPCR or next generation sequencing.
Proficient in biological sample handling as needed (i.e. tissue, blood, biofluid, etc.).
Data analysis, visualization, and reporting skills utilizing various software applications.
Excellent written and oral communication skills.
Highly skilled in visualization tools, SharePoint, Microsoft Office (Word, PowerPoint, Excel, Visio, Project).
Experience with development under FDA regulated environment is a plus.
Experience with data analysis in JMP, R, and python is a plus.
Hybrid Work Model:This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.Â
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com
A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.
Please visit our career page at:Â http://www.guardanthealth.com/jobs/
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