Mayo Clinic is seeking Histology Technicians and Histotechnologists (HT/HTL) to join a dynamic and collaborative team within Anatomic Pathology. Opportunities are available across multiple specialized laboratory areas, including:

Histology
Frozen Section/Surgical Pathology
Immunohistochemistry (IHC)
Renal Pathology

Each lab is offering unique workflows, techniques, and clinical impact.

The Anatomic Pathology Laboratories at Mayo Clinic process a high volume of complex specimens, including hundreds of thousands of paraffin-embedded blocks and over one million slides annually. Specimens include surgical, autopsy, and research material. Our laboratories take pride in contributing to accurate patient diagnoses and advancing scientific knowledge through collaboration with pathologists, clinicians, and research investigators.

Visit the Clinical Labs career site to watch a brief video of Dane discussing a life-changing career in Histology at Mayo Clinic.

As an HT/HTL, you will play a critical role in preparing high-quality slides for pathologist review. Responsibilities may include embedding, microtomy, cryotomy, special staining, immunohistochemical techniques, and handling of fresh and complex specimens. The work requires attention to detail, adaptability, and a commitment to quality and patient care.

In addition, you will:

Support training and onboarding of students and new employees
Collaborate across multidisciplinary teams to ensure timely and accurate results
Contribute to a respectful, inclusive, and team-oriented work environment
Adapt to the unique demands and workflows of different subspecialty laboratories

Mayo Clinic offers extensive opportunities for professional growth and career advancement within Anatomic Pathology. Whether you are interested in developing technical expertise across multiple lab areas or specializing in a particular discipline, this role provides a strong foundation for long-term career development.

Don’t miss the opportunity to be part of a team dedicated to excellence in patient care, innovation, and laboratory medicine.

Histology Technician / Histotechnologist (HT/HTL)

As a Histology Technician or Histotechnologist, you will perform a variety of technical procedures to prepare high-quality microscopic slide preparations used by pathologists for diagnostic and prognostic evaluation.

These procedures may include:

Specimen accessioning and identification
Specimen processing and embedding
Microtomy techniques, including:
- Paraffin
- Frozen (cryotomy)
- Plastic sections
Routine Hematoxylin and Eosin (H&E) staining
Special stains
Immunofluorescence
Immunohistochemical (IHC) staining
In situ hybridization

*Individuals hired to this position are required to complete 2 years in this position before becoming eligible to apply to other positions within Mayo Clinic.

**These positions are ineligible for visa sponsorship. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program**

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights

Medical: Multiple plan options.
Dental: Delta Dental or reimbursement account for flexible coverage.
Vision: Affordable plan with national network.
Pre-Tax Savings: HSA and FSAs for eligible expenses.
Retirement: Competitive retirement package to secure your future.

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Learn more about this Employer on their Career Site

Histology Technician or Histotechnologist (HT/HTL) - Anatomic Pathology