Setidegrasib Launch Lead (NSCLC), US Oncology

About Astellas

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.

Are you driven to make a real difference in the lives of patients?

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

Purpose & Scope

The U.S. Setidegrasib Launch Lead, NSCLC is responsible for leading U.S. commercial launch strategy and execution readiness for setidegrasib (A3082) in non-small cell lung cancer, a key oncology pipeline asset. This role will partner closely with cross-functional teams and co-creation affiliates to shape insight-driven launch plans, stakeholder engagement strategies, and commercial priorities that support a competitive U.S. launch and maximize long-term brand value. Responsibilities may evolve beyond NSCLC based on brand and business needs.

Role and Responsibilities

Develop and lead the U.S. commercial launch strategy and integrated launch plan for setidegrasib in NSCLC, including launch objectives, critical success factors, key milestones, governance, and cross-functional execution roadmap.
Translate patient, customer, scientific, biomarker/testing, pathway, market access, and competitive insights into clear brand priorities, business recommendations, and launch execution choices.
Shape U.S. brand positioning, messaging, and core launch materials in partnership with medical, legal, regulatory, market access, sales, training, agency, and global/co-creation partners.
Lead cross-functional launch readiness across key workstreams, including marketing, medical, access, sales, training, analytics, diagnostics/biomarker strategy, operations, and supply, ensuring alignment with Astellas launch excellence expectations.
Develop external stakeholder and customer engagement strategies for priority audiences, including HCPs, key external experts, patient advocacy organizations, pathways, accounts, and other relevant oncology stakeholders.
Partner with market access and account teams to support pricing, reimbursement, payer, distribution/channel, and account-level launch planning for the U.S. market.
Establish launch performance metrics, dashboards, feedback loops, and business review cadence to monitor readiness and early launch performance, identify risks, and optimize execution.
Ensure all launch planning and external engagement activities comply with Astellas policies, Ethics and Compliance standards, and applicable laws and regulations governing interactions with HCPs, HCOs, and patient organizations.

Qualifications

Required Qualifications

Bachelor’s degree required
Significant U.S. pharmaceutical or biotechnology commercial experience, with demonstrated success in oncology marketing, launch planning, or brand strategy.
Direct experience supporting or leading U.S. product launch preparation, including integrated launch planning, cross-functional readiness, customer strategy, and launch execution.
Strong understanding of the U.S. oncology market, including HCP engagement, treatment pathways, biomarker/testing dynamics, payer/access considerations, and the competitive landscape.
Proven ability to translate market, customer, patient, scientific, and competitive insights into clear strategic choices, commercial plans, and executional priorities.
Demonstrated ability to lead cross-functional teams and influence senior stakeholders across marketing, medical, market access, sales, regulatory, legal, analytics, and global partners.
Strong knowledge of pharmaceutical industry compliance requirements and ability to ensure activities are conducted in accordance with company policies and applicable laws and regulations.

Preferred Qualifications

U.S. commercial experience in Lung Cancer
HCP Marketing experience

Location and Working Environment

This position is based in Northbrook, Illinois. Remote work from anywhere in the US is available.

At Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines.

What awaits you at Astellas?

Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.

Our Organizational Values and Behaviors

Values: Innovation, Integrity and Impact sit at the heart of what we do.

Behaviors: We come together as ‘One Astellas’, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.

Salary Range

$161,928 - $243,500 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations.) Flexible pay grade level based on candidate background and skillset.

Benefits:

Medical, Dental and Vision Insurance
Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
401(k) match and annual company contribution
Company paid life insurance
Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
Long Term Incentive Plan for eligible positions
Company fleet vehicle for eligible positions
Referral bonus program

#LI-TD

Learn more about this Employer on their Career Site