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Job Description
About the role:
At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.
Join Takeda as a Scientist, Process Chemistry where you will play a crucial role in advancing our mission by pushing the boundaries of synthetic chemistry and driving innovation in drug development. You will also work on stimulating scientific and technical challenges in a highly collaborative and empowering environment. As part of the SMPD team, you will report to Director, Process Chemistry TMA.
Our Synthetic Molecule Process Development (SMPD) team develops robust, sustainable, and cost-effective processes for the manufacture of new synthetic molecule pharmaceuticals. We are committed to achieving and controlling the highest standards of purity and quality in all our products.
How you will contribute:
Contribute to the preparation of technical reports, patent applications, and scientific publications to communicate research findings.
Design and develop laboratory proof of concept for new, concise synthetic routes to challenging drug substance targets.
Stay informed about new technologies and trends in process chemistry and drug development, integrating relevant advancements into project strategies.
Develop safe, efficient and robust chemical processes for drug substance manufacture, enduring compliance with regulatory standards.
Collaborate with our Pharmaceutical Sciences colleagues and our external supply chain partners to bring new experimental medicines to the clinic.
Understand project timelines and deliverables and plans/coordinates project work accordingly with departmental, functional, and external stakeholders.
Provide technical leadership to project teams within area of expertise and commit resources to execute specific project tasks.
Review, interpret and communicate data cross-functionally within CMC and project teams.
Plan and implement resolutions to technical problems/issues.
Represent functional area on GCT project teams by communicating activities from designated functional area to project team.
Support local and global initiatives which may include leading initiatives or work stream.
Serve as a technical resource for junior staff and leverages expertise in laboratory technology as a functional resource/trainer.
Independently design and execute experiments and report results.
Help develop project strategy and communicate complex data/decisions within department and cross functionally as necessary.
Build and maintain relationships with key vendors and assist with technical aspects of vendor negotiations.
Analyze manufacturing issues and coordinate potential resolution with the CMC team.
Minimum Requirements/Qualifications:
Bachelors degree in chemistry, biology, pharmacy, engineering or related pharmaceutical science and 8+ years relevant industry experience.
Masters degree in chemistry, biology, pharmacy, engineering or related pharmaceutical science; 6+ years relevant industry experience.
PhD in chemistry, biology, pharmacy, engineering or related pharmaceutical science; 0+ years relevant industry experience.
Bachelors or Masters: Extensive experience in CMC pharmaceutical development for active pharmaceutical ingredients and drug products under cGMP's.
Sound knowledge of current Good Manufacturing Practices (cGMP).
Previous experience with the use of contract facilities.
Experience in working in a multi-disciplinary team environment.
PhD: Demonstrated mastery of subject or area related to field.
Able to troubleshoot critical issues or problems, and determine causes and possible solutions.
Expresses oneself clearly and concisely within team; documents issues and/or concerns concisely with colleagues; adjust communication style as appropriate for the audience; timely and effectively communicate issues to supervisor; technical writing skills to support authorship of internal technical documents.
Capture organizational knowledge; improve solutions, processes, and deliverables through use of information; improve information capital by contributing experience, theories, deliverables, and models for others to use.
Time management within individual, departmental, and corporate goals and timelines; management of internal and external resources (vendors).
Demonstrated involvement in professional community evidenced by presentation of scientific posters or lectures at professional conferences or events.
Organic chemistry lab-based research experience; Advanced proficiency with typical analytical tools (e.g. NMR, UV, IR, HPLC); Proficiency with utilizing typical literature searching techniques to solve organic chemistry problems.
More about us:
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
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Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
Boston, MAU.S. Base Salary Range:
$108,500.00 - $170,500.00The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
